SyntheX

About:

SyntheX is a biotechnology company reimagining precision therapeutics with new drug discovery technologies focused on protein modulation.

Website: http://www.synthexlabs.com/

Twitter/X: SyntheX_Labs

Top Investors: IndieBio, 8VC, Bristol-Myers Squibb, SOSV, Oriza Ventures

Description:

SyntheX expands the druggable proteome using synthetic biology-driven drug discovery platforms. The platforms rely on empirical intracellular selection to discover protein interaction modulators. These can discover compounds that disrupt a specific protein-protein interaction (PPI), or achieve the inverse, and bring an E3 ubiquitin ligase and a neosubstrate of interest together to achieve functional protein degradation. In addition to external discovery collaborations, the platforms have generated an internal oncology pipeline focused on unique mechanisms of action around genetically validated targets.