Bellerophon Therapeutics

About:

Bellerophon focused on developing innovative products combining novel drugs and devices in the treatment of cardiopulmonary diseases.

Website: http://www.bellerophon.com/

Top Investors: New Mountain Capital, ARCH Venture Partners, Venrock, 5AM Ventures, Aravis Ventures

Description:

Bellerophon Therapeutics LLC is a clinical stage biotherapeutics company focused on developing innovative therapies at the intersection of drugs and devices that address significant unmet medical needs in the treatment of cardiopulmonary and cardiac diseases. Two of the company's product candidates are based on its proprietary pulsatile nitric oxide delivery device, INOpulse®, and are in Phase 2 clinical trials – one for the treatment of PAH and a second for the treatment of PH-COPD. The company's third product candidate, bioabsorbable cardiac matrix (BCM), is an injectable device currently undergoing a feasibility clinical trial, which is a CE mark registration trial in the European Union and is comparable to a Phase 2 trial in U.S. drug development, for the prevention of cardiac remodeling and subsequent congestive heart failure following acute myocardial infarction (heart attack).