Ascendis Pharma

About:

Ascendis Pharma built a high-value pipeline that aims to change the clinical treatment paradigms.

Website: http://ascendispharma.com

Twitter/X: AscendisPharma

Top Investors: Royalty Pharma, RA Capital Management, OrbiMed, Sofinnova Investments, Sofinnova Partners

Description:

Ascendis Pharma has built a high value pipeline with the aim of changing clinical treatment paradigms. Using our innovative TransCon prodrug technology platform, we continue to identify new opportunities addressing areas of high unmet medical need. TransCon is applicable to all drug classes, and is currently being used to create superior prodrugs of proteins, peptides and small molecules. Depending on choice of TransCon Carrier, either systemic or localized drug exposure is achieved, while dosing frequency is determined by the choice of TransCon Linker. The prodrugs are new chemical entities with new patent life. Product development process is de-risked, as the prodrugs release the active component in its native and unmodified form, maintaining the original drug’s well known mode of action.