Pathios Therapeutics

About:

Pathios Therapeutics is a biotech company focused on the development of therapies for autoimmune diseases and cancer.

Website: https://pathiostherapeutics.com

Top Investors: Innovate UK, Bristol-Myers Squibb, Brandon Capital, Canaan Partners, Medical Research Commercialisation Fund (MRCF)

Description:

Pathios Therapeutics is a biotech company focused on the development of therapies for autoimmune diseases and cancer. Pathios Therapeutics concentrates on the development of small molecule inhibitors targeting the pH-sensing G protein-coupled receptor GPR65. These inhibitors aim to counteract the immunosuppressive polarization of immune cells, such as tumor-associated macrophages, mediated by GPR65. This polarization is stimulated by the acidic tumor microenvironment commonly found in various cancers.